First Word in greater Fontsize By default the textlines are aligned to the bottom of all letters, independent from their sizes. If you want all text aligned to the top of the biggest letter, than choose the command \highbox{any text}{sizecommand}:

the LaTeXcode

\newlength{\normalheight} 
\setlength{\normalheight}{7pt} 
\newsavebox{\mybox} 
\newcommand{\highbox}[2]{%
\savebox{\mybox}{#2#1}%
\raisebox{\normalheight-\ht\mybox}{#2#1}}

An example:
\highbox{Hello,}{\Huge}